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The Micro-Biomedical Laboratory focuses on the development and application of micro-scaled devices based on MEMS and microfluidic technology for bio-engineering, biotechnology, and biomedical sciences.

Major research topics are i) large-scale cell culture platforms for advanced bio-manufacturing in bio-pharmaceutical industry and stem cell therapy, and ii) device/instruments to study cellular mechanics and mechanobiology of adherent cells.

Selected Publications

A. YekrangSafakar, A. Acun, J. W. Choi, E. Song, P. Zorlutuna, and K. Park, "Hollow microcarriers for large-scale expansion of anchorage-dependent cells in a stirred bioreactor," Biotechnology and Bioengineering, 2018

A. Mehrnezhad and K. Park, "Multi-frequency optomechanical stiffness measurement of single adherent cells on a solid substrate with high throughput." Analytical Chemistry, 2017

C. Danielson, A. Mehrnezhad, A. YekrangSafakar, and K. Park, "Fabrication and characterization of self-folding thermoplastic sheets using unbalanced thermal shrinkage," Soft Matter, 23, 4169, 2017.

M. Holley, N. Nagarjan, C. Danielson, P. Zorlutuna, and K. Park, "Development and characterization of muscle-based actuators for self-stabilizing swimming biorobots," Lab on a Chip, vol. 16, 3473, 2016.

















K. Park, A. Mehrnezhad, E. Corbin, and R. Bashir, "Optomechanical measurement of the stiffness of single adherent cells," Lab on a Chip, vol. 15, pp. 3460-3464, 2015.










K. Park, L. Millet, N. Kim, H. Li, X. Jin, G. Popescu, N. Aluru, K.J. Hsia, and R. Bashir, "Measurement of adherent cell mass and growth", Proceedings of the National Academy of Sciences, 107(48), 20691, 2010 (Impact factor=9.77, http://bit.ly/VsOkAg).









 V. Chan, K. Park, M. B. Collens, H. Kong, T. A. Saif, and R. Bashir, "Development of miniaturized walking biological machines", Scientific Reports published by Nature Publishing Group, 2, 2012 (http://bit.ly/Z29njS).








K. Park, J. Jang, D. Irimia, J. Sturgis, J. Lee, J. P. Robinson, M. Toner, and R. Bashir, "Living cantilever arrays for characterization of mass of single live cells in fluids", Lab on a Chip, 8, 1034, 2008 (cover article, Impact factor=6.48, http://bit.ly/Z2bLXT).









L. J. Millet, E. A. Corbin, R. Free, K. Park, H. J. Kong, W. P. King, and R. Bashir, "Mass measurement of patterned hydrogels with MEMS mass sensors", Small, 8, 2562, 2012 (Inside front cover, impact factor=7.33, http://bit.ly/120Xqut).








K. Park, N. Kim, D.T. Morisette, N. Aluru, and R. Bashir, "Resonant MEMS mass sensors for measurement of micro-droplet evaporation", Journal of Microelectromechanical Systems, 21, 702, 2012 ( Impact factor=2.16, http://bit.ly/SJsmuj).